RNA-Directed DNA Polymerase

An enzyme that synthesizes DNA on an RNA template. It is encoded by the pol gene of retroviruses and by certain retrovirus-like elements. EC 2.7.7.49.

Also Known As:

Reverse Transcriptase; RNA Transcriptase; Revertase; DNA Polymerase, RNA Directed; DNA Polymerase, RNA-Dependent; RNA Dependent DNA Polymerase; RNA Directed DNA Polymerase; DNA Polymerase, RNA-Directed; RNA-Dependent DNA Polymerase; Deoxynucleotide-triphosphate:DNA deoxynucleotidyltransferase (RNA-directed)

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Transferases: 6589
    - Phosphotransferases: 42769
      - Nucleotidyltransferases: 29
        DNA Nucleotidyltransferases: 4
        DNA-Directed DNA Polymerase: 1706
        RNA-Directed DNA Polymerase: 8825
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Viral Proteins: 4250
    - Viral Structural Proteins: 171
      - Nucleocapsid Proteins: 749
        Viral Core Proteins: 50
        pol Gene Products: 38
        RNA-Directed DNA Polymerase: 8825
    - Viral Nonstructural Proteins: 70
      - Viral Replicase Complex Proteins: 5
        pol Gene Products: 38
        RNA-Directed DNA Polymerase: 8825
    - Retroviridae Proteins: 7
      - pol Gene Products: 38
        RNA-Directed DNA Polymerase: 8825

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Disease

Drug/Important Bio-Agent (IBA)